Inflamation and is affects on the body
Inflammation in the body is a normal reaction of the white blood cells of the body to protect us from infection caused by harmful bacteria, viruses and from any other unwanted substances entering our body. During the process the white blood cells release some chemicals in order to fight with these infections. For instance, when we get a cold, the fever is a form of inflammation which helps to eliminate all the harmful effects of the infecting virus. However, there are some inflammations in the body that disturbs the balance of the body and may cause diseases.
What Causes Inflammation in the Body?
A poorly balanced diet that consists of processed foods, refined flours, high sugar content and various types of inflammatory fats can give rise to inflammation. Some kind of infection caused by virus, bacteria or parasites. Sometimes these infections are hidden and do not get identified easily. Allergens enter the body through food or from the environment. Adverse effects of toxic substances like pesticides or harmful chemicals and any forms of stress, be it psychological, physical, or emotional. Cortisol, also known as stress hormones, are released into the body because of stress. When there is a rise in the levels of the cortisol, it causes inflammation.
Read more at Buzzle: http://www.buzzle.com/articles/inflammation-in-the-body.html
What is the difference between chronic inflammation and acute inflammation?Acute inflammation - starts rapidly (rapid onset) and quickly becomes severe. Signs and symptoms are only present for a few days, but in some cases may persist for a few weeks.
What happens during acute inflammation? Within a few seconds or minutes after tissue is injured, acute inflammation starts to occur. The damage may be a physical one, or might be caused by an immune response.
Examples of diseases, conditions, and situations which can result in acute inflammation include: acute bronchitis, infected ingrown toenail, sore throat from a cold or flu, a scratch/cut on the skin, exercise (especially intense training), acute appendicitis, acute dermatitis, acute tonsillitis, acute infective meningitis, acute sinusitis, or a blow.
Chronic inflammation - this means long-term inflammation, which can last for several months and even years. It can result from:
Failure to eliminate whatever was causing an acute inflammation
An autoimmune response to a self antigen - the immune system attacks healthy tissue, mistaking it (them) for harmful pathogens.
A chronic irritant of low intensity that persists
Examples of diseases and conditions with chronic inflammation include: asthma, chronic peptic ulcer, tuberculosis, rheumatoid arthritis, chronic periodontitis, ulcerative colitis and Crohn's disease, chronic sinusitis, and chronic active hepatitis,
some cancers, atherosclerosis, hay fever and type 1 Diabetes - inflammation in various parts of the body are likely if the diabetes is not well controlled.
Inflammation needs to be well regulated.
What happens during acute inflammation? Within a few seconds or minutes after tissue is injured, acute inflammation starts to occur. The damage may be a physical one, or might be caused by an immune response.
Three main processes occur before and during acute inflammation:
Arterioles, small branches of arteries that lead to capillaries that supply blood to the damaged region dilate, resulting in increased blood flow
The capillaries become more permeable, so fluid and blood proteins can move into interstitial spaces (spaces between cells).
Neutrophils, and possibly some macrophages migrate out of the capillaries and venules (small veins that go from a capillary to a vein) and move into interstitial spaces. A neutrophil is a type of granulocyte (white blood cell), it is filled with tiny sacs which contain enzymes that digest microorganisms. Macrophages are also a type of white blood cells that ingests foreign material.
Klaus Ley, M.D., a scientist at the La Jolla Institute for Allergy & Immunology, reported in a study published in Nature that neutrophils are the human body's first line of defense; they are the main cells that protect us from bacterial infections. Their protective function is a positive one, however, they also have inflammatory properties that may eventually lead to heart disease and several autoimmune diseases, such as lupus. Effectively manipulating neutrophils is vital in disrupting inflammatory diseases.
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